Four children and a woman were killed on Wednesday in a regime barrel bomb attack on Hama province, the local media center reported.
The attack on the Islamic State-held village of Al-Nashmi also left dozens wounded. Further aerial bombing also targeted the towns of Taybat al-Imam and Kafr Zita in Hama.
In turn, rebels pounded the village of Qubbat al-Kraidi with mortar fire.
The Hama News Center also reported 1,000 people were displaced after their village was destroyed in Taizin al-Jadeeda.
Meanwhile, Syria opposition officials on Wednesday criticized UN envoy Staffan de Mistura after he announced he would choose the opposition delegation to UN-led talks in Geneva if they failed to do so.
De Mistura Tuesday said the talks previously scheduled for February 8 had been postponed until February 20 to give the opposition more time to present a united delegation.
He also warned that if they had not done so by February 8 he would "select the delegation in order to make sure that it can be as inclusive as possible." The opposition rejected the comments as "unacceptable."
This article was edited by The Syrian Observer. Responsibility for the information and views set out in this article lies entirely with the author.